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Lipitor

Brand- Name Lipitor Generic Name Atorvastatin Company Pfizer Disease/Medical Use Cholesterol First Approval Date Dec-1996

Atorvastatin If you have high cholesterol, you may not even know it. People with high cholesterol usually have no symptoms. So you could be at risk even if you’re feeling fine. But a plain blood test can help you and your doctor learn whether your cholesterol is higher than it should be.

If you have high cholesterol, you're not alone. More than 1 in 5 adults in the United States has high cholesterol. High cholesterol is one of many possible factors for heart disease. High cholesterol can lead to a heart attack or stroke.

If you have high cholesterol, the first step should be to make meaningful changes in your eating habits and to exercise. Hopefully, diet and exercise alone will be enough. However, for 2 out of 3 people with high cholesterol, diet and exercise may not be enough and a cholesterol-lowering medicine such as LIPITOR may also be necessary.

Along with diet and exercise, LIPITOR is proven to lower "bad" cholesterol by 39%-60% Atorvastatin calcium is a synthetic lipid-lowering agent. Atorvastatin is an inhibitor of 3 hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis.

Atorvastatin calcium is a white to off-white crystalline powder that is insoluble in aqueous solutions of pH 4 and below. Atorvastatin calcium is very slightly soluble in distilled water, pH 7.4 phosphate buffer, and acetonitrile, slightly soluble in ethanol, and freely soluble in methanol.

Lipitor tablets for oral administration contain 10, 20, or 40 mg atorvastatin and the following inactive ingredients: calcium carbonate, USP candelilla wax, FCC croscarmellose sodium, NF hydroxypropyl cellulose, NF lactose monohydrate, NF magnesium stearate, NF microcrystalline cellulose NF, Opadry White YS-1-7040 (hydroxyl propyl methylcellulose, polyethylene glycol, talc, titanium dioxide)polysorbate 80, NF simethicone emulsion.