The Royal Pharmaceutical Society of Great Britain (RPSGB) is the statutory narrow and professional body for pharmacists in England, Scotland and Wales. It has its head office at 1, Lambeth High Street, in the Borough of Lambeth in London. The society also has offices in Cardiff and Edinburgh. The publishing trade of the society - RPS Publishing - operates two divisions The Pharmaceutical Press which publishes textbooks, and PJ Publications, which publishes the weekly specialized journal The Pharmaceutical Journal and the monthly Hospital Pharmacist.

The main objective of the RPSGB is to lead, regulate (as a Statutory instrument) develop and endorse the pharmaceutical profession. All pharmacists in Great Britain (about 44,000) must be registered with the Society. The Society is curious amongst healthcare regulators in that it has its individual inspectorate. To become a member of the Society an individual must typically have completed an MPharm or (before 1997) a BPharm or BSc (pharmacy) degree, 45 weeks of pre-registration training and pass the registration examination. This gives them the correct to use the title MRPharmS and perform as a pharmacist in Great Britain. Fellowships (FRPharmS) may moreover be awarded.

The Pharmaceutical Society of Great Britain was founded on April 15, 1841 by William Allen FRS, Jacob Bell, Daniel Hanbury, John Bell and additional London chemists and druggists, at a meeting in the Crown and Anchor Tavern, Strand, London. William Allen was its first President, and the society rapidly took premises at 17 Bloomsbury Square, London where a School of Pharmacy was recognized in which botany and materia medical were a significant part of the students’ curriculum. In 1843, Queen Victoria decided the Society its Royal Charter. In 1988, Queen Elizabeth II decided that the title "Royal" should be granted to the society.